眼科

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小梁消融术联合白内障超声乳化手术和房角分离治疗原发性闭角型青光眼的初步探索

张思瑶  厉君  林利  唐琼燕  叶长华  段宣初  林丁   

  1. 410015 长沙,中南大学爱尔眼科学院 长沙爱尔眼科医院
  • 收稿日期:2018-07-24 出版日期:2019-07-25 发布日期:2019-07-30
  • 通讯作者: 林丁,Email:dlinoph@163.com

Preliminary exploration of trabectome combined with phacoemulsification and goniosynechialysis in the treatment of primary angle-closure glaucoma
 

ZHANG Si-yao, LI Jun, LIN Li, TANG Qiong-yan, YE Chang-hua, DUAN Xuan-chu, LIN Ding.   

  1. Aier School of Ophthalmology, Changsha Aier Hospital, Central South University, 410015 Changsha, Hunan, China
  • Received:2018-07-24 Online:2019-07-25 Published:2019-07-30
  • Contact: LIN Ding, Email: dlinoph@163.com

摘要:

 目的 观察小梁消融术联合白内障超声乳化手术和房角分离治疗合并白内障的原发性闭角型青光眼(PACG)的有效性和安全性。设计 回顾性病例系列。研究对象 具有青光眼滤过性手术联合白内障超声乳化手术指征的PACG合并白内障的患者16例。方法 16例患者术中行白内障超声乳化加人工晶状体植入和房角分离手术,再行小梁消融术。小梁消融范围为鼻侧90°~120°。术后随访6个月。主要指标 眼压,降眼压药物数量,术后并发症。结果 16例完成达6个月随访者14例(87.5%)。术前眼压平均(33.4±12.4)mmHg,术后6个月(13.3±1.8)mmHg。术前用降眼压药平均(2.1±0.5)种,术后6个月(0.5±0.7)种(P=0.000)。术中消融小梁网时均出现一过性前房积血,术后2~10天自行吸收;1例术后出现暂时性眼压升高;1例虹膜前粘连。16例患者均未行二次青光眼手术。结论 小样本量短期随访显示,小梁消融术联合白内障超声乳化及房角分离对具有行滤过性手术联合白内障手术指征的PACG合并白内障患者,具有降眼压、减少降眼压药物数量的作用,长期疗效尚需进一步验证。(眼科,2019, 28: 285-288)

关键词: 原发性闭角型青光眼, 白内障, 小梁消融术

Abstract:

Objective To observe the safety and efficacy of trabectome combined with phacoemulsification and goniosynechialysis for the patients with primary angle-closure glaucoma (PACG) combined with cataract. Design Retrospective case series. Participants Sixteen patients who has indication of glaucoma filtering surgery combined with phacoemulsification were included in this study. Methods Trabectome combined with phacoemulsification and goniosynechialysis were performed after eye examinations. During the operation, phacoemulsification and intraocular lens implantation combined with goniosynechialysis were performed first, and then trabectome was performed. The trabecular ablation ranged from 90 to 120 degrees on the nasal side. The follow-up was 6 months. Main Outcome Measures Intraocular pressure (IOP), the number of glaucoma medications, postoperative complications. Results All of the 16 patients, 14(87.5%) were followed up for 6 months. IOP was reduced from (33.4±12.4) mmHg to (13.3±1.8) mmHg with statistical significance (P =0.000). Meanwhile the number of glaucoma medications was reduced from (2.0±0.5) to (0.5±0.7) at six months with statistical significance (P=0.000). When trabecular meshwork was ablated during operation, there was no other serious complication occurred except for hyphema. One case had a temporary IOP elevation. One case had the anterior synechia. Conclusion Trabectome combined with phacoemulsification and goniosynechialysis can reduce IOP and the number of glaucoma medications significantly for the patients with PACG combined with cataract, who has indication of glaucoma filtering surgery combined with phacoemulsification. Long-term efficacy needs further verification. (Ophthalmol CHN, 2019, 28: 285-288)

Key words: primary angle-closure glaucoma, cataract, trabectome